Oxegen AKG Learn

What is Oxegen AKG?
In order to explain Oxegen AKG, we must first begin with L-Arginine, a dietary supplement which has typically been used to stimulate the production of nitric oxide in the body.* The problem, however, is during the digestive process L-Arginine (a positively charged amino acid) will bind with any negatively charged amino acid – resulting in portions of L-Arginine correctly binding with Glutamate (a negatively charged amino acid, which stimulates nitric oxide production), while other portions incorrectly bind with different elements, leading to either (i) the beneficial intent of L-Arginine being lost, or (ii) the creation of a free-radical (which is damaging to the body).*

It is for this reason that Oxegen AKG utilizes Arginine Alpha-Ketoglutarate (AKG) instead of simple L-Arginine. Oxegen AKG mimics the biomolecular, physiological and chemical reaction your body naturally goes through during the L-Arginine/nitric oxide conversion process, resulting in a single target-specific formula with just one task – producing nitric oxide.* But before nitric oxide production can occur, Oxegen AKG must arrive in the small intestine (lower GI) intact.

In order to ensure Oxegen AKG survives the harsh environment of the stomach and arrives in the small intestine intact – ready for absorption via the villi (tiny hair-like projections) which take up nutrients – Oxegen AKG utilizes SurSorb™ Sustained Release Technology (SRT). For simplicity purposes, think of the villi as being "coded" (like a lock), absorbing only certain nutrients (which hold the key). Without the correct key, the villi will not initiate absorption. Oxegen AKG is formulated with a transfer enzyme which unlocks the villi key (allowing absorption) and triggers Endothelial Nitric Oxide Synthase (eNOS) – the enzyme which stimulates the natural production of nitric oxide.

As nitric oxide levels increase, nitro vasodilation (the widening of blood vessels) occurs and greater blood flow, nutrients, amino acids, and oxygen are delivered throughout the body and into the cells. The nitro vasodilator benefits of nitric oxide on smooth muscle cells have been demonstrated in controlled clinical trials. One such trial evaluated the contribution of nitric oxide to metabolic coronary vasodilation in the human heart. Results showed both a (i) 50% increase in blood flow and (ii) 68% reduction in coronary vascular resistance.¹
In addition to vasodilation, a secondary benefit of nitric oxide is its ability to act as its own self-defense mechanism, lubricating the endothelial lining of blood vessels like Teflon – keeping things from sticking to the blood vessel wall.² Thus, the presence of nitric oxide itself not only exhibits vasodilation, but further aids in the lubrication of endothelial blood vessel walls.²

Studies have further shown endothelium-dependent vasodilation may become impaired by the presence of oxygen free radicals – inactivating or degrading intracellular availability of L-Arginine, the precursor of Nitric Oxide Synthase (NOS).³ It is for this reason Oxegen AKG is formulated with Vitamin C (as calcium ascorbate) to help deliver both sustained delivery of powerful antioxidants and greater bioavailability, while helping to ensure less stomach upset for individuals sensitive to Vitamin C.⁴

What is Nitric Oxide?
Nitric Oxide (NO) is a simple molecule consisting of two atoms – nitrogen and oxygen – and made by a process known as Endothelial Nitric Oxide Synthase (eNOS). Nitric oxide is a gas made by our blood vessels which causes blood vessels to relax (or widen), leading to greater blood flow, nutrients, amino acids and oxygen to travel throughout the body and into the cells.⁵

Is Oxegen AKG Scientifically Proven?
The breakthrough science behind the nitro vasodilator effect of Oxegen AKG is so unique, three American researchers were awarded the Nobel Prize™ in Medicine for discovering how nitric oxide affects blood flow in the body.

How Can Oxegen AKG Have So Many Benefits?
Because Oxegen AKG works by stimulating the natural production of nitric oxide to help widen blood vessels, Oxegen AKG works with the entire circulatory system – where blood goes, Oxegen AKG goes.*

What is SurSorb?
SurSorb™ Sustained-Release Technology (SRT) helps ensure the full benefits and efficacy of Oxegen AKG are delivered to the cells by discouraging degradation in the stomach – delivering maximum absorption from the minimum dosage, so you take far fewer tablets, resulting in much greater value!*

Who Should Try Oxegen AKG?
Anyone who is concerned with blood flow, lean muscle, oxidized fat burning, endurance, stamina, energy, sexual performance, enhanced low-carb dieting and exercise – but not at risk.* (Please see Warnings below for those who should not take Oxegen AKG).

Warnings: Do not use if you are pregnant or nursing, if you are at risk of or are being treated for diabetes or low blood pressure. Consult your healthcare professional before use if you are being treated for high blood pressure, diabetes, liver, thyroid, psychiatric disease or taking sildenafil citrate. Use this product with caution if you have renal or hepatic failure or have a history of cold sores. Caffeine or ephedrine based products may reduce the effectiveness. Do not use with products that contain Ephedra as they may act as a vasoconstrictor reducing benefit. Do not take your dosage after 3:00pm. Although this supplement contains no stimulants, it may keep you awake. High doses of arginine may be toxic and overuse may cause diarrhea, nausea, headache or allergic reaction.

1 Circulation. 1995;92:320-326
2 News Hour with Jim Lehrer (PBS); 10-12-1998
3 Circulation. 1998;97:363-368
4 Book;Vitamin C The Future is Now; by Jeffery Bland, Ph.D
5 Ann Intern Med, Feb 1994; 120: 227 - 237

*The claims made about Oxegen AKG on or through this site have not been evaluated by the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other healthcare professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

Copyright 2004 Innovative Product Solutions Group. All trademarks, service marks, word marks and logos appearing on this site are the sole property of Innovative Product Solutions Group.

What is Oxegen AKG? In order to explain Oxegen AKG, we must first begin with L-Arginine, a dietary supplement which has typically been used to stimulate the production of nitric oxide in the body.* The problem, however, is during the digestive process L-Arginine (a positively charged amino acid) will bind with any negatively charged amino acid – resulting in portions of L-Arginine correctly binding with Glutamate (a negatively charged amino acid, which stimulates nitric oxide production), while other portions incorrectly bind with different elements, leading to either (i) the beneficial intent of L-Arginine being lost, or (ii) the creation of a free-radical (which is damaging to the body).* It is for this reason that Oxegen AKG utilizes Arginine Alpha-Ketoglutarate (AKG) instead of simple L-Arginine. Oxegen AKG mimics the biomolecular, physiological and chemical reaction your body naturally goes through during the L-Arginine/nitric oxide conversion process, resulting in a single target-specific formula with just one task – producing nitric oxide.* But before nitric oxide production can occur, Oxegen AKG must arrive in the small intestine (lower GI) intact.
In order to ensure Oxegen AKG survives the harsh environment of the stomach and arrives in the small intestine intact – ready for absorption via the villi (tiny hair-like projections) which take up nutrients – Oxegen AKG utilizes SurSorb™ Sustained Release Technology (SRT). For simplicity purposes, think of the villi as being "coded" (like a lock), absorbing only certain nutrients (which hold the key). Without the correct key, the villi will not initiate absorption. Oxegen AKG is formulated with a transfer enzyme which unlocks the villi key (allowing absorption) and triggers Endothelial Nitric Oxide Synthase (eNOS) – the enzyme which stimulates the natural production of nitric oxide. As nitric oxide levels increase, nitro vasodilation (the widening of blood vessels) occurs and greater blood flow, nutrients, amino acids, and oxygen are delivered throughout the body and into the cells. The nitro vasodilator benefits of nitric oxide on smooth muscle cells have been demonstrated in controlled clinical trials. One such trial evaluated the contribution of nitric oxide to metabolic coronary vasodilation in the human heart. Results showed both a (i) 50% increase in blood flow and (ii) 68% reduction in coronary vascular resistance.¹ In addition to vasodilation, a secondary benefit of nitric oxide is its ability to act as its own self-defense mechanism, lubricating the endothelial lining of blood vessels like Teflon – keeping things from sticking to the blood vessel wall.² Thus, the presence of nitric oxide itself not only exhibits vasodilation, but further aids in the lubrication of endothelial blood vessel walls.² Studies have further shown endothelium-dependent vasodilation may become impaired by the presence of oxygen free radicals – inactivating or degrading intracellular availability of L-Arginine, the precursor of Nitric Oxide Synthase (NOS).³ It is for this reason Oxegen AKG is formulated with Vitamin C (as calcium ascorbate) to help deliver both sustained delivery of powerful antioxidants and greater bioavailability, while helping to ensure less stomach upset for individuals sensitive to Vitamin C.⁴
What is Nitric Oxide? Nitric Oxide (NO) is a simple molecule consisting of two atoms – nitrogen and oxygen – and made by a process known as Endothelial Nitric Oxide Synthase (eNOS). Nitric oxide is a gas made by our blood vessels which causes blood vessels to relax (or widen), leading to greater blood flow, nutrients, amino acids and oxygen to travel throughout the body and into the cells.⁵
Is Oxegen AKG Scientifically Proven? The breakthrough science behind the nitro vasodilator effect of Oxegen AKG is so unique, three American researchers were awarded the Nobel Prize™ in Medicine for discovering how nitric oxide affects blood flow in the body. How Can Oxegen AKG Have So Many Benefits? Because Oxegen AKG works by stimulating the natural production of nitric oxide to help widen blood vessels, Oxegen AKG works with the entire circulatory system – where blood goes, Oxegen AKG goes.* What is SurSorb? SurSorb™ Sustained-Release Technology (SRT) helps ensure the full benefits and efficacy of Oxegen AKG are delivered to the cells by discouraging degradation in the stomach – delivering maximum absorption from the minimum dosage, so you take far fewer tablets, resulting in much greater value!* Who Should Try Oxegen AKG? Anyone who is concerned with blood flow, lean muscle, oxidized fat burning, endurance, stamina, energy, sexual performance, enhanced low-carb dieting and exercise – but not at risk.* (Please see Warnings below for those who should not take Oxegen AKG). Warnings: Do not use if you are pregnant or nursing, if you are at risk of or are being treated for diabetes or low blood pressure. Consult your healthcare professional before use if you are being treated for high blood pressure, diabetes, liver, thyroid, psychiatric disease or taking sildenafil citrate. Use this product with caution if you have renal or hepatic failure or have a history of cold sores. Caffeine or ephedrine based products may reduce the effectiveness. Do not use with products that contain Ephedra as they may act as a vasoconstrictor reducing benefit. Do not take your dosage after 3:00pm. Although this supplement contains no stimulants, it may keep you awake. High doses of arginine may be toxic and overuse may cause diarrhea, nausea, headache or allergic reaction.