Frequently Asked 
Questions...


As with any dietary supplement, you may have questions regarding CholestSorb and CholestSorb PLUS, and as such, we have endeavored through the following pages to address your most frequently asked questions. If after reading this material you require additional information, please do not hesitate to contact us at 1-866-888-8208, Monday through Friday: 10 a.m. to 5p.m., or write to: CholestSorb 4045 Sheridan Avenue #363, Miami Beach, FL 33140
What is cholesterol?
Cholesterol is largely misunderstood. Cholesterol is a waxy, fat-like substance, also called lipid (fat) alcohols, and a vital building block of the body that must be kept in balance. Important tissues and organs such as the brain, spinal cord, kidneys, and adrenal glands all utilize cholesterol, and it is essential in the manufacture of nerve tissue, bile, and many hormones. Low-density lipoproteins (LDL) "bad" cholesterol and high-density lipoproteins (HDL) "good" cholesterol both transport cholesterol through the bloodstream.1

What is bad cholesterol (LDL)?
Low-density lipoproteins (LDL), carry cholesterol through the bloodstream for participation in the cell-building needs of the body, but leave behind excess deposits called plaque, which accumulate on the interior arterial walls.1

What is good cholesterol (HDL)?
High-density lipoproteins (HDL), remove excess deposits of plaque from the arterial walls allowing the free flow of blood through the body. The excess LDL "bad" cholesterol is transported by the HDL "good" cholesterol to the liver where it can be removed.1

What is High Cholesterol?
According to the American Heart Association, total cholesterol levels of 240 mg/dL or above are considered high, and levels from 200 to 239 mg/dL are considered borderline high, meaning more than one-in-three Americans have unhealthy cholesterol levels.1

How do different cholesterol levels indicate heart health?
The following chart by the American Heart Association establishes total cholesterol levels as an important indicator for heart health.

Total Cholesterol Levels

Less than 200 mg/dL

Desirable

200–239 mg/dL

Borderline High Risk

240 mg/dL and over

High Risk

What is CholestSorb?
CholestSorb is a dietary supplement that helps (neutralizes) cholesterol in the stomach, thereby preventing new cholesterol from reaching the bloodstream, and formulated for those individuals wishing help manage their cholesterol through natural means.* By blocking new cholesterol, CholestSorb allows the body to naturally rid itself of old cholesterol.* Because CholestSorb works in the stomach – and not the liver – there are no side effects common to more aggressive alternatives for managing healthy cholesterol.*

How does CholestSorb work?
CholestSorb works to help block (neutralize) new cholesterol in the stomach from the food you eat before reaching the bloodstream.* The saponins in Esterin process alfalfa extract (bind) with new cholesterol in the stomach, preventing its absorption and allowing the body to naturally rid itself of the old cholesterol.*

Why are bad cholesterol levels so high in Americans?
A contemporary diet (high in saturated and trans fats) combined with a lifestyle which lacks exercise can result in an imbalance in which HDL "good" cholesterol cannot "clean" all of the excess LDL "bad" cholesterol. This imbalance may cause plaque to remain and cause hardening of the arteries, a higher risk of heart disease, and a host of other problems.*

Why not simply take an alfalfa supplement instead of CholestSorb?
CholestSorb contains a concentrated saponin extract of alfalfa not found in conventional alfalfa supplements. You would have to consume barrels of alfalfa to equal the effective amount of saponins found in Esterin Process Alfalfa! Only CholestSorb puts the power of non-toxic, concentrated saponins in a form that allows the body to help rid itself of bad cholesterol naturally and effectively.*

How much does CholestSorb and CholestSorb PLUS help influence LDL "bad" cholesterol levels?
In a published peer-reviewed article about Esterin Alfalfa, studies showed a decrease in LDL "bad" cholesterol levels between 21% up to 37% in some individuals.2*

How much does CholestSorb and CholestSorb PLUS help influence HDL "good" cholesterol levels?
In a published peer reviewed article about Esterin Alfalfa, studies showed an increase in HDL "good" cholesterol levels between 26% up to 52% in some individuals.13*

How much can CholestSorb and CholestSorb PLUS help influence my lipid profile?
The scientific results on both LDL and HDL cholesterol show the active ingredients in CholestSorb may influence the HDL/LDL ratio between 63% up to 96% in some individuals.13*

How do other anti-cholesterol agents typically work?
Most anti-cholesterol agents act on the liver – after cholesterol absorption from the stomach. Since the liver is the body’s cholesterol production center, these anti-cholesterol agents work to limit cholesterol synthesis in the liver – which may cause side effects and require changes in dietary habits as well as impact the production of "good" cholesterol.*

How do CholestSorb and CholestSorb PLUS compare to Phytosterol supplements?
CholestSorb has been shown in clinical studies to influence  LDL "bad" cholesterol levels between 21% up to 37%, while simultaneously influencing HDL "good" cholesterol levels between 26% up to 52% in some individuals13, with no change in diet or exercise.2* Phytosterol formulas have been shown to reduce LDL"bad" cholesterol levels up to 10% and 24% with a very restrictive low-fat diet and daily exercise.12,14*

How and when should I take CholestSorb or CholestSorb PLUS?
You should take one tablet of CholestSorb with your meals, or as directed by your physician. Each dosage works for a four to six hour period depending upon your metabolism. It is important to take CholestSorb with your meals.

Can I use CholestSorb or CholestSorb PLUS on a sugar-restricted diet?
CholestSorb contains no sugar, starch, yeast, artificial flavors, preservatives, or artificial colors. It is sodium-free, contains no wheat or soy products, and is free of dairy and meat or meat by-products. CholestSorb is K (Kosher) approved and vegetarian appropriate.*

Are there any side effects associated with CholestSorb?
None when taken as directed.*

What is ExploTab®
By utilizing the same technology that pharmaceutical companies use to ensure their tablets disintegrate uniformly and timely in the stomach, ExploTab ensures the cholesterol binding ingredient – Esterin Process Alfalfa Saponins – in CholestSorb are readily available in your stomach to bind with the food you eat.* This rapid dissolution means you get optimum performance from CholestSorb.*

What are the active ingredients in CholestSorb & CholestSorb PLUS?
All CholestSorb formulas utilize the non-toxic, patented, clinically proven Esterin Process Alfalfa extract, PLUS the added benefits of non-flush Niacin (Inositol Hexanicotinate) and Standardized Garlicto help manage healthy cholesterol levels.*

How does Niacin help lower cholesterol?
Niacin inhibits cholesterol synthesis in the liver while also appearing to increase its degradation.5* Elevated blood levels of Lipoprotein A have been studied as an independent risk factor for heart health.6* Niacin appears to play a role by altering the function of Lipoprotein A-I, reducing synthesis of Lipoprotein A-II 8 – which is believed to result in an elevation of HDL levels.4* Non-Flush Niacin works by decreasing the liver’s production of Very Low-Density Lipoprotein (VLDL) – a relatively large particle comprised mainly of triglycerides and cholesterol – which helps lower LDL (bad) cholesterol while raising HDL (good) cholesterol by decreasing its degradation rate.* CholestSorb PLUS with Niacin is complete with a full day’s dosage of Niacin, so additional Niacin supplementation is unnecessary.*

Can the niacin in CholestSorb PLUS with Niacin cause skin irritations?
No. CholestSorb PLUS utilizes only "non-flush" (inositol Hexanicotinate) niacin.8-11*

Is the non-flush niacin in CholestSorb PLUS with Niacin safe?
CholestSorb PLUS with Niacin utilizes non-flush Inositol Hexanicotinate niacin (IHN), which is clinically documented to be safe and free of side effects at doses up to 4 grams.8* In fact, patients in one clinical study were given doses ranging from 600 to 1,800 mg daily with no observed side effects, while approximately 1/3 of another group of patients receiving regular niacin (nicotinic acid) reported one or more of the following symptoms: flushing, nausea, vomiting, giddiness and weakness.8* Additionally, IHN patients tolerated dosages of 3 to 4 times larger than the nicotinic acid group without side effects.8* Numerous other investigators studying the use of dosages of IHN in the range of 4 grams daily have reported no adverse reactions.8-11*

How does Garlic help lower cholesterol?
Garlic possesses certain observed compounds attributed to cholesterol lowering, which – when isolated – have demonstrated a lowering effect on LDL.8* Specifically, Garlic contains approximately 1% alliin, which converts to allicin in the presence of the enzyme allinase (ESCOP, 1997).* Pharmacological research on garlic has shown that garlic inhibits lipid peroxidation and reduces serum cholesterol and lipid levels.18,-22* Garlic's effects on blood pressure and as an antioxidant from free radicals have also been studied.* In fact, studies have shown that standardized odorless garlic helps reduce LDL Cholesterol levels, mean triglyceride levels, and mean serum cholesterol levels.16,17* CholestSorb PLUS with Garlic is complete with a full day’s dosage of Garlic, so additional Garlic supplementation is unnecessary.*

Warning: Consult a Health Care Professional before use if you are currently under medical care or are taking prescription drugs. Pregnant or lactating women should consult a health care professional before using any product.

1  www.americanheart.org
2  Esterin Alfalfa Saponins. Journal of American Nutraceuticals Association: Vol. 3, No. 4 2/22/2001.
3  Inositol Hexaniacinate. Alternative Medicine Review: 1998 June.
4  Certified in accordance with the National Nutritional Foods Association.
5  El-Enein AMA, Hafez YS, Salem H, Abdel M. The role of nicotinic acid and inositol hexaniacinate as anticholesterolemic and antilipemic agents. Nutr Reports Int 1983;28:899-911.
6  Bays H, Dujovne CA, Mays JB. Elevated lipoprotein (a) levels as the single treatable atherosclerotic risk factor in patients with coronary artery disease. J Ky Med Assoc 1993;91:498-500.
7  Alderman JD, Pasternak RC, Sacks FM, et al. Effect of a modified, well-tolerated niacin regimen on serum total cholesterol, high density lipoprotein cholesterol and the cholesterol to high density lipoprotein ratio. Am J Cardiol 1989;64:725-729.
8  Holti G. An experimentally controlled evaluation of the effect of inositol nicotinate upon the digital blood flow in patients with Raynaud's phenomenon. J Int Med Res 1979;7:473-483.
9  Dorner V, Fischer FW. The influence of m-inositol Hexanicotinate ester on the serum lipids and lipoproteins. Arzneim-Frosch 1961;11:110-113.
10  Ring EFJ, Porto LO, Bacon PA. Quantitative thermal imaging to assess inositol nicotinate treatment for Raynaud's syndrome. J Int Med Res. 1981;9:393-400.
11  Sunderland GT, JJF Belch, RD Sturrock, et al. A double blind randomized placebo controlled trial of Hexopal in primary Raynaud's disease. Clin Rheum 1988;7:46-49.
12  Stevinson, C. Pittler MH, Ernst E. Garlic for Treating Hypercholesterolemia. A meta-analysis of randomized clinical trials. Annals of Internal medicine 2000; 133(6):420-429.
13  Merck Index, 11th Edition 1989 Pages 263, 401 Review published in the JANA (Journal of American Nutraceuticals Association - Winter 2001).
14  Comparative analysis - Phytosterols: Jones et al. ,Am. J. Clin. utr. 1999; 69: 1144 -50. Study Review - Effect of dietary phytosterols on cholesterol metabolism. Journal of medicine 1999; 107: 588 - 594.
15  American Botanical Council www.herbalgram.org Garlic Monograph
16  Clinical study (Mader, 1990) American Botanical Council www.herbalgram.org Garlic Monograph
17  Mader, F.H. 1990. Treatment of hyperlipidemia with garlic-powder tablets. Evidence from the German Association of General Practitioners' multicentric placebo-controlled double-blind study. Arzneimforsch 40(10):1111–1116
18  Brosche et al., 1990; Bordia, 1981; Jain et al., Mader, 1990; Rotzsch et al,., 1992 Brosche, T. and D. Platt. 1990. Knoblauch als pflanzlicher lipidsenker. Neuere untersuchungen mit einem standardisierten knoblauchtrockenpulver-pr‰parat [Garlic as phytogenic antilipemic agent. Recent studies with a standardized dry garlic powder substance]. Fortschr Med 108(36):703–706.
19  Bordia, A. et al. 1977. Effect of essential oil of onion and garlic on experimental atherosclerosis in rabbits. Atherosclerosis 26(3):379–386.
20  Jain, R.C. and D.B. Konar. 1978. Effect of garlic oil in experimental cholesterol atherosclerosis. Atherosclerosis 29(2):125–129.
21  Rotzsch W., V. Richter, F. Rassoul, A. Walper. 1992. [Postprandial lipemia under treatment with Allium sativum. Controlled double-blind study of subjects with reduced HDL2-cholesterol] [In German]. Arzneimforsch 42(10):1223–1227.
22  Mader, F.H. 1990. Treatment of hyperlipidemia with garlic-powder tablets. Evidence from the German Association of General Practitioners' multicentric placebo-controlled double-blind study. Arzneimforsch 40(10):1111–1116.
23  Circulation. 1995;92:320-326.
24  Pharmacotherapy 21(7):797-806, 2001


*The claims made about CholestSorb on or through this site have not been evaluated by the United States Food and Drug Administration and are not approved to diagnose, treat, cure or prevent disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other healthcare professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.

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